Protein targeting pathway mastering biology

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Protein Targeting

Proteins need be sent to the correct organelle within the cell or sometimes need to be exported out of the cell into the extracellularspace to carry out their function. To make sure the proteins arrive at the correct destination, the polypeptide will have a molecularlabel (specific amino acid sequence) that will ensure the protein is delivered to a specific location.

Within the cell itself, there are various systems that help to deliver the proteins, produced in the process of translation, to reach their end terminus.

Overview of Cellular Protein Transportation Systems

• Proteins intended for the cytoplasm or the post-translational delivery to organelles such as the nucleus or peroxisome are produced on free ribosomes.
• Proteins intended for the membrane or the exterior of the cell are produced on ribosomes attracted on the rough endoplasmicreticulum (RER).

At each stage of the process of the translation, the protein being produc Protein Targeting SUJI